Endocrine Abstracts

Introduction: VEGFA is considered the main angiogenic factor in adipose tissue. It is believed that a low angiogenic capacity may decrease the adipogenic potential and consequently promotes adipocyte hypertrophy, which in turn, is closely related to insulin resistance (IR). Oestradiol (E2) is a regulator of the VEGFA gene and a protector against obesity. However nothing is known about the E2 effects on VEGF adipocyte production, and its consequence for ce...